Effect of Leukocyte Antibodies on the Fate In Vivo of Indium-i 1 1-Labeled Granulocytes
نویسندگان
چکیده
The effect of different leukocyte antibodies on the fate in vivo of granulocytes is not known. Thus, the optimum in vitro serologic tests to determine a safe and effective granulocyte transfusion or to diagnose immune destruction of granulocytes in other clinical situations have not been identified. We have studied the effect of granulocyte agglutinating (GA), granulocytotoxic (GC), and lymphocytotoxic (IC) antibodies on the intravascular recovery and half-life (t’/2) and the extravascular localization of Indium1 1 1 -granulocytes in 50 patients. GA antibodies caused reduced granulocyte recovery and t’/2 in three of three
منابع مشابه
Effect of leukocyte antibodies on the fate in vivo of indium-111-labeled granulocytes.
The effect of different leukocyte antibodies on the fate in vivo of granulocytes is not known. Thus, the optimum in vitro serologic tests to determine a safe and effective granulocyte transfusion or to diagnose immune destruction of granulocytes in other clinical situations have not been identified. We have studied the effect of granulocyte agglutinating (GA), granulocytotoxic (GC), and lymphoc...
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